Deuterium Depletion in Life Science
Depletion of body deuterium (D) can simply be achieved by consumption or prolonged administration of deuterium-depleted water (DDW) and nutrients deficient in D. It was therefore postulated that D-depletion would have therapeutic use in patients with cancer and other neoplastic diseases. In subsequent toxicology studies DDW appeared to be completely safe and non-toxic when given to mice in place of regular water for several months. Following preclinical safety and efficacy studies, a Phase II double blind randomized clinical trial was initiated to evaluate the potential usefulness of therapeutic efficacy and safety of DDW in patients with prostate tumor.
Expert opinions
„I think, people will soon realize that water is the most important foodstuff, drink, important element for us to live, and therefore to choose the proper water is very important…that would be offered, I hope, by HYD.”

Prof. Roman Zubarev
Karolinska Institute, Stockholm, Sweden
„Deuterobolomics is now a field that is covering the physiology and biochemistry of deuterium….It is actually a responsibility of physicians of these days to know about these mechanisms, because they exist without question.”

Prof. Boros G. László
Kalifornia Egyetem, Los Angeles, USA
„At the molecular level deuterium and proton are not behaving at the same manner….When we will understand exactly at molecular level the mechanism, the field will grow, because it has an enormous potential and I am fully convinced after so many years of working on metabolism.”

Prof. Martha Cascante
Universitat de Barcelona, Spain
„Almost all people should know this scientific movement and scientific success, this is clear.”
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Prof. Valentin Lobyshev
Lomonosov University, Moscow, Russia
„Metabolic water is depleted in deuterium and we think, that this has a lot of therapeutic benefit as far as enhancing the cell’s energetic capacity and stabilizing the DNA of the cell, which will give a therapeutic effect to cancer patients.”

Prof. Dominic D’Agostino
University of South Florida, Tampa, USA
„Deuterium depletion offers a more powerful but also milder means for efficient treatment and prevention of primarily tumorous diseases than any other therapy up to now. Application of preparations of reduced deuterium content can complement the medicines currently used in therapy and prevention, and can show higher efficiency than those.”

Gábor Somlyai PhD
General Manager of HYD Pharma Co
„Deuterium depleted water is regularly recommended to our patients for tumor prevention and also as supplementary therapy. Water with reduced deuterium content helps in all phases of the disease and can hence be recommended any time.”

Dr. Erika Balaicza
Internist, Head Physician at Activ-Naturmed, Hungary
„In recent years, there are many companise have begun to under take DDW business and research in China. Especially some hospitals are now developing clinical studies in cancer patients. As an adjuvant therapy for tumor,DDW has shown a beneficial effect. I expect that it eventually can be developed a new kind of anti-cancer medicine."

Fengsong Cong PhD
Shanghai Jiao Tong University, China



HYD LLC for Cancer Research and Drug Development offers the sterile distilled water with 25 ppm deuterium content to universities and research institutes. HYD LLC wishes to promote research in this field in Hungary and abroad, and provides DDW 25, its product for research purposes, at a moderate price.
5th International Congress on Deuterium Depletion
The 5th International Congress on Deuterium Depletion took place from 22 to 23 April 2026 in Budapest. The two-day conference aimed to present the latest research findings and clinical applications of deuterium depletion, and to define the current and future role of this method in cancer research and prevention, as well as in the treatment of other, primarily metabolic and mental diseases, and in aging research. The conference provided a broad scientific forum for both Hungarian and foreign researchers and medical professionals to share their latest results. By bringing together the world’s leading scientists in the field, the conference served not only as a scientific platform but also as an opportunity for networking and establishing collaborations.
To watch the conference presentations, click here.
To watch the interviews, click here.
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